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Disease Tolerance as a Defence Strategy against Glomerular Disease
11 Oktober
14:00 Uhr - 15:30 Uhr

We are very pleased to invite you to the KFO329 seminar held by Pierre-Louis Tharaux (Paris Cardiovascular Centre – PARCC, INSERM & Université Paris-Descartes) on Disease Tolerance as a Defence Strategy against Glomerular Disease scheduled for Thursday, October 11, 2018 - 2.00 p.m. s.t. in the Mediathek of the CMMC Research Building, Robert-Koch-Str. 21, 50931 Cologne. Please find the seminar announcement attached.
Thomas Benzing (Speaker of the KFO 329) and Paul Brinkkötter (Scientific Coordinator of the KFO 329) are hosting the guest speaker. If you would like to meet with Pierre-Louis Tharaux before or after his talk, please contact paul.brinkkoetter@uk-koeln.de.
Short introduction of Pierre-Louis Tharaux and his research focus
Pierre-Louis Tharaux is Research Professor at INSERM, The Paris Cardiovascular Centre – PARCC and appointed by the Division of Nephrology, Georges Pompidou European Hospital, AP-HP, Paris.
He obtained an MD at the Paris Descartes University in Paris (1998). He was registered as nephrologist in 1998 and obtained a PhD in Cell Biology in 2000 (Pierre et Marie Curie University, Paris). He received postgraduate training for two years at Duke University Medical Center, Durham, NC (Thomas M Coffman) and the University of North Carolina (Bev Koller). He recently spent a year as Senior Fellow at the Freiburg Institute for Advanced Studies, Freiburg, Germany.
Pierre-Louis Tharaux performs high risk/high potential benefit research in areas of major medical need in Nephrology.
Research in his laboratory involves analysis of mouse vascular and renal pathophysiology with translation to clinical studies, with a particular emphasis on genes or pathways implicated in disease tolerance.
His work covers:
- GPCRs and RTK signaling, multi-omic integration in kidney and vascular cells in accelerated hypertensive and diabetes-induced ageing, focal segmental glomerulosclerosis (FSGS), Crescentic Glomerulonephritides (CGN).
His research aims at promoting of tolerance of the kidney and the microcirculation to immune injury (vasculitides with CGN) and to hypertensive and metabolic injury (diabetes).
- Drug repositioning and new drug development for hypertensive thrombotic microangiopathy, microvascular auto-immune diseases and sickle cell disease
- Involvement of neutrophils and endothelial cells in Sickle Cell Nephropathy and Vasculopathy.

An overview of life science seminars taking place at the Life Science Campus Cologne is provided at: www.life-science-vortraege.uni-koeln.de.
We are looking forward to welcoming you and interested members of your institution.